Transgenesis upgrades for Drosophila melanogaster

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Transgenesis upgrades for Drosophila melanogaster.

Drosophila melanogaster is a highly attractive model system for the study of numerous biological questions pertaining to development, genetics, cell biology, neuroscience and disease. Until recently, our ability to manipulate flies genetically relied heavily on the transposon-mediated integration of DNA into fly embryos. However, in recent years significant improvements have been made to the tr...

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Aconitase and Developmental EndPointsasEarly IndicatorsofCellularToxicity Induced by Xenobiotics in Drosophila Melanogaster

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Drosophila melanogaster

The region of the second chromosome of Drosophila melanogaster defined by DJ(2R)vgB was screened for recessive lethal and visible mutations. Fifty-eight new recessive alleles fall into 17 complementation groups. Many new vg alleles were also isolated in a screen for new ng deficiencies. The breakpoints of the new ug deficiencies were nonrandomly distributed. The distal breakpoints of twelve of ...

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Drosophila Melanogaster

$ 3 mm long dipteran ( ̄y), commonly known as the fruit ̄y. $ Adult ̄y is yellow-brown in colour, with oval wings and rust-red eyes. $ y180 Mb genome, as four chromosomes X/Y, 2, 3 and 4. $ Genome sequence substantially completed 24 March 2000. $ 120 Mb euchromatic region of genome comprises 13 601 predicted genes. $ Has made signi®cant contribution to understanding of development. $ Large-scale P...

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ژورنال

عنوان ژورنال: Development

سال: 2007

ISSN: 1477-9129,0950-1991

DOI: 10.1242/dev.005686